Ahmed Muhammad Zeeshan Primary Author mixed material bibliography Semarang Universitas Negeri Semarang 2021 e English

Artikel Jurnal

hlm : 154-160 Abstract Purpose: This study aimed to predict the binding affinity, orientation, and physical interaction between limonene and fat mass and obesity-associated protein. Methods: The mechanism of limonene and protein association was explored by molecular docking, a bioinformatic tool. The association results were compared with the reported results of the anti-obesity drug such as orlistat and with the flavonoids. AutoDock Vina tools were used for the molecular docking of limonene with fat mass and obesity-associated protein. PyMol and Discovery Studio Visualizer was used to visualize the results of this docking. Result: The binding affinity of limonene was higher (Least negative G) than the orlistat and flavonoids such as Daidzein, Exemestane, Kaempherol, Letrozole, And Rutin. Novelty: In this study, the limonene can alleviate obesity by interacting with the fat mass and obesity-associated protein. This inhibitory interaction was more significant as compared to other reported phytochemicals and drugs. Informatika SJI 24077658 Perpustakaan Teknik UPI YAI SJI V8N1 May 2021 SJI3a-020 Perpustakaan FT UPI YAI SJI V8N1 May 2021 SJI3b-020 Perpustakaan FT UPI YAI SJI V8N1 May 2021 SJI_V8N1_May_2021.png.png 59007 2023-02-08 16:01:09 2023-02-08 16:01:09 machine generated