Abstract
Diabetic retinopathy (DR) is eye diseases caused by diabetic mellitus or sugar diseases. If DR is detected in early stage, the blindness that follow can be prevented. Ophthalmologist or eye clinician usually decide the stage of DR from retinal fundus images. Careful examination of retinal fundus images is time consuming task and require experienced clinicians or ophthalmologist but a computer which has been trained to recognize the DR stages can diagnose and give result in real-time manner. One approach of algorithm to train a computer to recognize an image is deep learning Convolutional Neural Network (CNN). CNN allows a computer to learn the features of an image, in our case is retinal fundus image, automatically. Preprocessing is usually done before a CNN model is trained. In this study, four preprocessing were carried out. Of the four preprocessing tested, preprocessing with CLAHE and unsharp masking on the green channel of the retinal fundus image give the best results with an accuracy of 79.79%, 82.97% precision, 74.64% recall, and 95.81% AUC. The CNN architecture used is Inception v3.